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H.I-1: (n.d.). Retrieved February 21, 2018, from https://editor.wix.com/html/editor/web/renderer/edit/f035c624-e36f-468c-a701-d5c6cb4e817a?metaSiteId=3e7d2f13-1716-4bbb-b9fb-1e5cf9371ab8&editorSessionId=27E615ED-5219-4CA0-A585-FB4A0762E919

H.I-2:Safety Implications of Microneedle Patches for Influenza Vaccine. (2017, September 09). Retrieved February 21, 2018, from http://www.thevaccinereaction.org/2017/08/safety-implications-of-microneedle-patches-for-influenza-vaccine/

H.I-3:Microneedle Image Gallery. (n.d.). Retrieved February 21, 2018, from http://drugdelivery.chbe.gatech.edu/gallery_microneedles.html

H.I-4:Kerr, J. (2013, April 05). Bird flu in China - experts respond. Retrieved February 21, 2018, from https://www.sciencemediacentre.co.nz/2013/04/04/bird-flu-in-china-expert-responds/

H.I-5:Campos, A. (2014, January 11). UNICEF reveals terror as conflict rages in Central African Republic. Retrieved February 22, 2018, from https://www.irishmirror.ie/news/world-news/unicef-reveals-terror-conflict-rages-3013024

H.I-6:The "mesh" of microtubule connectors helps new cells to be born. (n.d.). Retrieved February 21, 2018, from http://serious-science.org/mesh-of-microtubule-connectors-helps-new-cells-be-born-3905

H.I-7:World Map. (n.d.). Retrieved February 21, 2018, from https://www.momentaryink.com/products/world-map?variant=3819030042

H.I-8:New Flexible Microneedle Patch Promises Faster Medication Delivery -Prescouter - Custom Intelligence, On-Demand. (2013, September 17). Retrieved February 21, 2018, from https://prescouter.com/2013/09/new-flexible-microneedle-patch-promises-faster-medication-delivery/

Content

H.C-1:Donnelly, R. F., McCrudden, M. T., Alkilani, A. Z., Larrañeta, E., McAlister, E., Courtenay, A. J., . . . Woolfson, A. D. (n.d.). Hydrogel-Forming Microneedles Prepared from "Super Swelling" Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery. Retrieved February 14, 2018, from http://journals.plos.org/plosone/article?id=:10.1371%2Fjournal.pone.0111547

H.C-2: Microneedle patches for vaccination in developing countries. (2015, November 18). Retrieved February 21, 2018, from https://www.sciencedirect.com/science/article/pii/S016836591530242X?via%3Dihub

H.C-3: Kendall, M. (n.d.). Demo: A needle-free vaccine patch that's safer and way cheaper. Retrieved February 21, 2018, from https://www.ted.com/talks/mark_kendall_demo_a_needle_free_vaccine_patch_that_s_safer_and_way_cheaper/up-next#t-799204

H.C-4: Microneedle patches for vaccination in developing countries. (2015, November 18). Retrieved February 21, 2018, from https://www.sciencedirect.com/science/article/pii/S016836591530242X?via%3Dihub

H.C-5: Kendall, M. (n.d.). Demo: A needle-free vaccine patch that's safer and way cheaper. Retrieved February 21, 2018, from https://www.ted.com/talks/mark_kendall_demo_a_needle_free_vaccine_patch_that_s_safer_and_way_cheaper/up-next#t-799204

H.C-6: Transdermal delivery of desmopressin using a coated microneedle array patch system. (2004, June 19). Retrieved February 21, 2018, from https://www.sciencedirect.com/science/article/pii/S0168365904001713

H.C-7: Depelsenaire, A. C., Meliga, S. C., McNeilly, C. L., Pearson, F. E., Coffey, J. W., Haigh, O. L., . . . Kendall, M. A. (2014, September). Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216316/

H.C-8: Painless micro-needle vaccine patch set for human trials this year. (2013, April 19). Retrieved February 21, 2018, from https://www.geek.com/news/painless-micro-needle-vaccine-patch-set-for-human-trials-this-year-1552729/

H.C-9: Kim, M., Yang, H., Kim, H., & Jung, H. (2014, February 24). Novel cosmetic patches for wrinkle improvement: retinyl retinoate‐ and ascorbic acid‐loaded dissolving microneedles. Retrieved February 21, 2018, from http://onlinelibrary.wiley.com/doi/10.1111/ics.12115/abstract

H.C-10: Painless micro-needle vaccine patch set for human trials this year. (2013, April 19). Retrieved February 21, 2018, from https://www.geek.com/news/painless-micro-needle-vaccine-patch-set-for-human-trials-this-year-1552729/

H.C-11: Painless micro-needle vaccine patch set for human trials this year. (2013, April 19). Retrieved February 21, 2018, from https://www.geek.com/news/painless-micro-needle-vaccine-patch-set-for-human-trials-this-year-1552729/

H.C-12: (n.d.). Retrieved February 21, 2018, from https://pure.qub.ac.uk/portal/en/persons/ryan-donnelly(7f46a524-c3a4-46a9-b347-834f0a3640f2).html

H.C-13: The Bill & Melinda Gates Foundation is the Largest LEED Platinum Non-Profit Building in the World. (2011, October 08). Retrieved December 14, 2017, from https://inhabitat.com/the-bill-melinda-gates-foundation-is-the-largest-leed-platinum-non-profit-building-in-the-world/

H.C-14: Paudel, K. S., Milewski, M., Swadley, C. L., Brogden, N. K., Ghosh, P., & Stinchcomb, A. L. (2010, July). Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995530/

H.C-15: Williams, S. C. (2013, June 18). Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690886/

H.C-16: V. (n.d.). Benefits. Retrieved February 21, 2018, from http://www.vaxxas.com/nanopatch-technology/benefits/

TIME-LINE

T.I-1:MOTION SICKNESS MINI PATCHES ANTI NAUSEA TRAVEL VOMITING PAIN RELIEF CAR SEA AIR (5) by Kangdi: Health & Personal Care. (n.d.). Retrieved December 13, 2017, from https://www.amazon.com/MOTION-SICKNESS-PATCHES-NAUSEA-VOMITING/dp/B01L4PUPJK

T.I-2:Patent US4921475 - Transdermal drug patch with microtubes. (n.d.). Retrieved December 13, 2017, from https://www.google.com/patents/US4921475

T.I-3:US5457041A - Needle array and method of introducing biological substances into living cells using the needle array. (n.d.). Retrieved February 21, 2018, from https://patents.google.com/patent/US5457041

T.I-4:US5457041A - Needle array and method of introducing biological substances into living cells using the needle array. (n.d.). Retrieved February 21, 2018, from https://patents.google.com/patent/US5457041

T.I-5:US6611707B1 - Microneedle drug delivery device. (n.d.). Retrieved February 21, 2018, from https://www.google.com/patents/US6611707?dq=microneedle%2Bpatents&hl=en&sa=X&ved=0ahUKEwj7i9m0qKvXAhVJ9GMKHeuOCY0Q6AEILzAB

T.I-6:US6256533B1 - Apparatus and method for using an intracutaneous microneedle array. (n.d.). Retrieved February 21, 2018, from https://patents.google.com/patent/US6256

T.I-7:US6256533B1 - Apparatus and method for using an intracutaneous microneedle array. (n.d.). Retrieved February 21, 2018, from https://www.google.com/patents/US6256533

T.I-8:Lee, J. W., Choi, S., Felner, E. I., & Prausnitz, M. R. (2011, January 04). Dissolving Microneedle Patch for Transdermal Delivery of Human Growth Hormone. Retrieved February 21, 2018, from http://onlinelibrary.wiley.com/doi/10.1002/smll.201001091/full

T.I-9:Mark Kendall demonstrates how the Nanopatch works to nurses at Port Moresby General Hospital. Papua New Guinea. (2012, December 01). Retrieved February 21, 2018, from https://collidecolumn.wordpress.com/2012/12/01/when-worlds-collide-44-vaccines-without-pain-and-needles-yipee/mark-kendall-demonstrates-how-the-nanopatch-works-to-nurses-at-port-moresby-general-hospital-papua-new-guinea/

T.C-1: Wood, C. D. (2012, November 18). Antimotion Sickness and Antiemetic Drugs. Retrieved February 15, 2018, from https://link.springer.com/article/10.2165/00003495-197917060-00003

T.C-2:Patent US4921475 - Transdermal drug patch with microtubes. (n.d.). Retrieved December 13, 2017, from https://www.google.com/patents/US4921475

T.C-3: Long-term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles. (2002, November 11). Retrieved December 13, 2017, from http://www.sciencedirect.com/science/article/pii/0264410X9390387D

T.C-4 :Patent US5457041 - Needle array and method of introducing biological substances into living cells using the needle array. (n.d.). Retrieved December 13, 2017, from https://www.google.com/patents/US5457041https://www.google.com/patents/US5457041

T.C-5:Patent US6611707 - Microneedle drug delivery device. (n.d.). Retrieved December 13, 2017, from https://www.google.com/patents/US6611707?dq=microneedle%2Bpatents&hl=en&sa=X&ved=0ahUKEwj7i9m0qKvXAhVJ9GMKHeuOCY0Q6AEILzAB

T.C-6:Patent US6256533 - Apparatus and method for using an intracutaneous microneedle array. (n.d.). Retrieved December 13, 2017, from https://www.google.com/patents/US6256533

T.C-7:Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery. (2005, April 01). Retrieved December 13, 2017, from http://www.sciencedirect.com/science/article/pii/S0168365905000568

T.C-8:Alibrandi, G., Coppolino, S., Micali, N., & Villari, A. (2003, April). Release from transdermal delivery systems. Application of a new non isothermic method to Trans-Ver-Sal patches. Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pubmed/?term=trans-ver-sal

T.C-9:Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery. (2005, April 01). Retrieved February 21, 2018, from http://www.sciencedirect.com/science/article/pii/S0168365905000568

T.C-10:Engineering of needle-free physical methods to target epidermal cells for DNA vaccination. (2005, September 01). Retrieved February 21, 2018, from http://www.sciencedirect.com/science/article/pii/S0264410X05008418 

T.C-11:Alibrandi, G., Coppolino, S., Micali, N., & Villari, A. (2003, April). Release from transdermal delivery systems. Application of a new non isothermic method to Trans-Ver-Sal patches. Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pubmed/?term=trans-ver-sal

T.C.-12:Lee, J. W., Choi, S., Felner, E. I., & Prausnitz, M. R. (2011, January 04). Dissolving Microneedle Patch for Transdermal Delivery of Human Growth Hormone. Retrieved February 21, 2018, from http://onlinelibrary.wiley.com/doi/10.1002/smll.201001091/full

T.C-13: Fear of Needles? Theres New Tech on the Way. (n.d.). Retrieved February 21, 2018, from https://www.bing.com/cr?IG=A8D886E418D94FB5B0A4D320AD1B34E2&CID=37A14425117268802C1F4FBB10DD695F&rd=1&h=kNFYxQDPIeBbxWaIKAD-uJInbiLhkyDiF0eOldHBl-Q&v=1&r=https%3a%2f%2fnews.nationalgeographic.com%2f2016%2f11%2fmark-kendall-explorer-moments-micro-spikes-deliver-vaccines%2f&p=DevEx,5036.1

T.C-14: Kim, M., Yang, H., Kim, H., & Jung, H. (2014, February 24). Novel cosmetic patches for wrinkle improvement: retinyl retinoate‐ and ascorbic acid‐loaded dissolving microneedles. Retrieved February 21, 2018, from http://onlinelibrary.wiley.com/doi/10.1111/ics.12115/full

T.C-15: Georgia Institute of Technology. (2011, November 02). Retrieved February 21, 2018, from http://www.rh.gatech.edu/news/340821/medical-device-innovation-georgia-tech-develops-technologies-solve-health-care-problems

T.C-16:Yu, J., Zhang, Y., Ye, Y., DiSanto, R., Sun, W., Ranson, D., . . . Gu, Z. (2015, June 17). Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. Retrieved February 21, 2018, from http://www.pnas.org/content/early/2015/06/17/1505405112

T.C-17: No items found - PubMed - NCBI. (n.d.). Retrieved February 21, 2018, from https://www.ncbi.nlm.nih.gov/pubmed/?term=Alzheimer%27s%2Bdisease%2Bmicroneedle%2Bpatch

T.C-18: Fear of Needles? There's New Tech on the Way. (2018, February 13). Retrieved February 21, 2018, from https://news.nationalgeographic.com/2016/11/mark-kendall-explorer-moments-micro-spikes-deliver-vaccines/

Content

A.C-1: Rolex Awards for Enterprise. (n.d.). Retrieved February 21, 2018, from http://www.rolexawards.com/profiles/laureates/mark_kendall

A.C-2: Microneedle patches for vaccination in developing countries. (2015, November 18). Retrieved February 21, 2018, from https://www.sciencedirect.com/science/article/pii/S016836591530242X?via%3Dihub

A.C-3:A novel microparticulate vaccine for melanoma cancer using transdermal delivery. (n.d.). Retrieved December 14, 2017, from http://www.tandfonline.com/doi/abs/10.3109/02652048.2011.559287

A.C.-4: Chen, M. C., Lai, K. Y., Ling, M. H., & Lin, C. W. (2018, January). Enhancing immunogenicity of antigens through sustained intradermal delivery using chitosan microneedles with a patch-dissolvable design. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/29109028

A.C.-5: Zaric, M., Becker, P. D., Hervouet, C., Kalcheva, P., Ibarzo, B., Cocita, C., . . . Klavinskis, L. S. (2017, December 28). Long-lived tissue resident HIV-1 specific memory CD8 T cells are generated by skin immunization with live virus vectored microneedle arrays. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/29056444

A.C.-6: Quana, F., Kimb, Y., Songc, J., Hwangf, H. S., Compansd, R. W., & And, M. R. (2013, September 01). Fu-Shi Quan. Retrieved December 14, 2017, from http://cvi.asm.org/content/20/9/1433.short

A.C.-7: Measles vaccination using a microneedle patch. (2012, October 05). Retrieved December 14, 2017, from http://www.sciencedirect.com/science/article/pii/S0264410X12013941

A.C-8:Friedlander, R. (2017, October 09). I Got the Kim Kardashian Vampire Facial. Retrieved February 21, 2018, from https://www.elle.com/beauty/makeup-skin-care/news/a14931/kim-kardashians-vampire-facial/

A.C.-9: Jung, D., Rejinold, N. S., Kwak, J. E., Park, S. H., & Kim, Y. C. (2017, November 01). Nano-patterning of a stainless steel microneedle surface to improve the dip-coating efficiency of a DNA vaccine and its immune response. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/28780461

A.C.-10: Park, K. Y., Kwon, H. J., Lee, C., Kim, D., Yoon, J. J., Kim, M. N., & Kim, B. J. (2017, September). Efficacy and safety of a new microneedle patch for skin brightening: A Randomized, split-face, single-blind study. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/28574158

A.C.-11: Lee, C., Yang, H., Kim, S., Kim, M., Kang, H., Kim, N., . . . Jung, H. (2016, August). Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/26648582

A.C.-12: Park, Y., Park, J., Chu, G. S., Kim, K. S., Sung, J. H., & Kim, B. (2015, July 21). Transdermal delivery of cosmetic ingredients using dissolving polymer microneedle arrays. Retrieved December 14, 2017, from https://link.springer.com/article/10.1007/s12257-014-0775-0

A.C.-13: KIM, S., LEE, J., KWON, H. B., AHN, B., & LEE, A. (2011, February 22). Greater Collagen Deposition with the Microneedle Therapy System Than with Intense Pulsed Light. Retrieved December 14, 2017, from http://onlinelibrary.wiley.com/doi/10.1111/j.1524-4725.2011.01882.x/full

A.C-14: Pires, Liliana R., et al. Human Vaccines & Immunother apeutics, Taylor & Francis, July 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4964821/.

A.C-15: “No items found - PubMed - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/pubmed/?term=Alzheimer%27s%2Bdisease%2Bmicroneedle%2Bpatch.

A.C-16: Yu, Jicheng, et al. “Microneedle-Array patches loaded with hypoxia-Sensitive vesicles provide fast glucose-Responsive insulin delivery.” Proceedings of the National Academy of Sciences, National Academy of Sciences, 17 June 2015, www.pnas.org/content/early/2015/06/17/1505405112.

A.C-17: Wallace, M, and M Pappagallo. “Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia.” Expert review of neurotherapeutics., U.S. National Library of Medicine, Jan. 2011, www.ncbi.nlm.nih.gov/pubmed/21158551.

Images

SOCIAL, LEGAL, ETHICAL ISSUES

S.C-1: Park, K. Y., Kwon, H. J., Lee, C., Kim, D., Yoon, J. J., Kim, M. N., & Kim, B. J. (2017, September). Efficacy and safety of a new microneedle patch for skin brightening: A Randomized, split-face, single-blind study. Retrieved December 14, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/28574158

S.C.-2: Microneedle patches: Usability and acceptability for self-vaccination against influenza. (2014, February 11). Retrieved December 15, 2017, from http://www.sciencedirect.com/science/article/pii/S0264410X1400139X

S.C.-3: Safety Implications of Microneedle Patches for Influenza Vaccine. (2017, September 09). Retrieved December 15, 2017, from http://www.thevaccinereaction.org/2017/08/safety-implications-of-microneedle-patches-for-influenza-vaccine/

S.C.-4:Safety Implications of Microneedle Patches for Influenza Vaccine. (2017, September 09). Retrieved December 15, 2017, from http://www.thevaccinereaction.org/2017/08/safety-implications-of-microneedle-patches-for-influenza-vaccine/

S.C.-5:Williams, Sarah C. P. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 18 June 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3690886/.

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Images

S.I-1: Face whitening cream Shopping Online In Pakistan. (n.d.). Retrieved February 20, 2018, from https://www.shoppingbag.pk/search/face-whitening-cream.html

S.I-2: Papua New Guinea. (n.d.). Retrieved February 20, 2018, from http://www.markrothschildphoto.com/papua-new-guinea/

Videos

S.V-1: How to use Microneedle Patch. (2017, February 16). Retrieved February 20, 2018, from

https://www.youtube.com/watch?v=j_X9_7niYlQ

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T.V-1:S. (2013, May 14). Microneedle technology: Oxford NanoDelivery. Retrieved February 21, 2018, from https://www.youtube.com/watch?time_continue=1&v=6idUWxtJ97g

T.V-2:G. (2017, June 27). Microneedle patches for flu vaccination prove successful in first human clinical trial. Retrieved February 21, 2018, from https://www.youtube.com/watch?v=msS04cMF8l0

T.V-3:B. (2013, October 09). How do microneedles deliver drugs? HD. Retrieved February 21, 2018, from https://www.youtube.com/watch?v=cNwVvcXLiWc

Videos

T.V

Images

INNOVATORS

I.I-1:(n.d.). Retrieved February 21, 2018, from https://myaccount.news.com.au/sites/couriermail/subscribe.html?sourceCode=CMWEB_WRE170_a_GGL&mode=premium&dest=http%3A%2F%2Fwww.couriermail.com.au%2Fbusiness%2Fvicechancellors-and-top-executives-at-queensland-universities-paid-12-million-a-year%2Fnews-story%2Fc0c0b31ac1dda1cdba6fe3241fba9f7b%3Fmemtype

I.I-2:News releases for journalists. (n.d.). Retrieved December 14, 2017, from http://www.ox.ac.uk/news-and-events/for-journalists

I.I-3:(n.d.). Retrieved December 14, 2017, from http://www.qub.ac.uk/Study/AHSS/Law_UG_2016/

I.I-4:Wonder 2017: The University of Nottingham opens its doors for new fun-filled community day. (2017, May 14). Retrieved December 14, 2017, from http://westbridgfordwire.com/wonder-2017-university-nottingham-opens-doors-new-fun-filled-community-day/

I.I-5:(n.d.). Retrieved December 14, 2017, from https://www.kcii.re.kr/ENG/index.asp

I.I-6:O'Callaghan, T. (2009, August 19). A patch to take the ouch out of shots. Retrieved December 14, 2017, from http://healthland.time.com/2009/08/19/a-patch-to-take-the-ouch-out-of-shots/

I.I-7:Procter & Gamble's Rome Offices Just Got Searched In A Tax Avoidance Probe. (n.d.). Retrieved December 14, 2017, from http://fortune.com/2016/07/07/procter-rome-tax-probe/

I.I-8:Georgia Institute of Technology. (2017, December 12). Retrieved December 14, 2017, from https://en.wikipedia.org/wiki/Georgia_Institute_of_Technology

I.I-9:The Bill & Melinda Gates Foundation is the Largest LEED Platinum Non-Profit Building in the World. (2011, October 08). Retrieved December 14, 2017, from https://inhabitat.com/the-bill-melinda-gates-foundation-is-the-largest-leed-platinum-non-profit-building-in-the-world/

Content

I.C-1:The University of Queensland. (n.d.). Retrieved February 21, 2018, from https://researchers.uq.edu.au/researcher/733

I.C-2:Carey, J. B., Pearson, F. E., Vrdoljak, A., McGrath, M. G., Crean, A. M., Walsh, P. T., . . . Moore, A. C. (n.d.). Microneedle Array Design Determines the Induction of Protective Memory CD8 T Cell Responses Induced by a Recombinant Live Malaria Vaccine in Mice. Retrieved December 14, 2017, from http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0022442

I.C-3: Reyes-Sandoval, A. (1970, January 01). Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches. Retrieved February 21, 2018, from https://ora.ox.ac.uk/objects/uuid%3A2155c639-bcc8-49e0-b415-a5d353aacba3

I.C-4: I.C-14:(n.d.). Retrieved December 14, 2017, from https://www.manufacturingchemist.com/news/article_page/Microneedle_drug_delivery_could_draw_blood_and_other_fluids_out_of_the_skin/93710queens college

I.C-5: Donnelly, R. F., McCrudden, M. T., Alkilani, A. Z., Larrañeta, E., McAlister, E., Courtenay, A. J., . . . Woolfson, A. D. (n.d.). Hydrogel-Forming Microneedles Prepared from "Super Swelling" Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery. Retrieved February 14, 2018, from http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0111547

I.C-6:Kim, M., Yang, H., Kim, H., & Jung, H. (2014, February 24). Novel cosmetic patches for wrinkle improvement: retinyl retinoate‐ and ascorbic acid‐loaded dissolving microneedles. Retrieved December 14, 2017, from http://www.coriumintl.com/http://www.freepatentsonline.com/6379324.html

I.C-7:Corium Inc. – Delivering Innovative Transdermal Solutions. (n.d.). Retrieved December 14, 2017, from http://www.coriumintl.com/http://www.freepatentsonline.com/6379324.html

I.C-8:Patent US7226439 - Microneedle drug delivery device. (n.d.). Retrieved December 14, 2017, from https://www.google.com/patents/US7226439 

I.C-9:Georgia Institute of Technology. (2017, June 27). Retrieved February 22, 2018, from http://www.news.gatech.edu/2017/08/24/microneedle-patches-flu-vaccination-successful-first-human-clinical-trial

I.C-10:The Bill & Melinda Gates Foundation is the Largest LEED Platinum Non-Profit Building in the World. (2011, October 08). Retrieved December 14, 2017, from https://inhabitat.com/the-bill-melinda-gates-foundation-is-the-largest-leed-platinum-non-profit-building-in-the-world/

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APPLICATION

Images

A.I-1:(n.d.). Retrieved February 21, 2018, from https://editor.wix.com/_partials/media-gallery-g5/1.523.0/index.html#/public

A.I.-2: (n.d.). Retrieved February 21, 2018, from https://editor.wix.com/_partials/media-gallery-g5/1.523.0/index.html#/public

A.I.-3: (n.d.). Retrieved February 21, 2018, from https://editor.wix.com/_partials/media-gallery-g5/1.523.0/index.html#/public

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